基于儒可夫斯基变换的涡轮钻具叶片设计及性能分析

为提高涡轮钻具叶片使用性能和创新叶片设计理论,提出了基于儒可夫斯基保角变换法与经典水力翼型相结合的涡轮钻具叶片设计新方法,以?127涡轮钻具叶片为研究对象,运用搭建的涡轮钻具叶型参数化设计平台和自主设计的涡轮钻具性能测试台架,完成了5种翼型的造型设计,研究了5种叶片流场性能,开展了设计叶片的性能测试实验,对比分析了设计叶片与塔里木油田某型在役?127涡轮叶片的实际效能。实验及仿真结果表明,基于新方法设计的NACA-0012翼型加厚叶片在600 r/min转速及15 L/s流量的设计工况下,其单级扭矩达5.83 N·m,较相同条件下某在役?127涡轮的单级扭矩提高约6.4%,级效率提高约1.16%,整体性能有了实质提升。     

电牵引采煤机PLC控制系统故障分析

主要分析国产电牵引采煤机控制系统中PLC电源故障,介绍输入回路、输出回路故障的分析、判断及排除方法。     

Microenvironment and related genes predict outcomes of patients with cervical cancer: evidence from TCGA and bioinformatic analysis

Cervical cancer (CESC) is one of the most common cancers and affects the female genital tract. Consistent HPV infection status has been determined to be a vital cause of tumorigenesis. HPV infection may induce changes to the immune system and limit the host’s immune response. Immunotherapy is therefore essential to improving the overall survival of both locally advanced and recurrent CESC patients. Using 304 relevant samples from TCGA, we assessed immune cell function in CESC patients to better understand the status of both tumor micro-environment cells and immune cells in CESC. Functional enrichment analysis, pathway enrichment analysis, and PPI network construction were performed to explore the differentially expressed genes (DEGs). The analysis identified 425 DEGs, which included 295 up-regulated genes and 130 down-regulated genes. We established that upregulation of CCL5 was correlated with significantly better survival, meaning that CCL5 expression could serve as a novel prognostic biomarker for CESC patients. We further focused on CCL5 as a hub gene in CESC, as it had significant correlations with increased numbers of several types of immune cells. Cell-type fractions of M1 macrophages were significantly higher in the high-immune-scores group, which was associated with better overall survival. Finally, we concluded that CCL5 is a promising prognostic biomarker for CESC, as well as a novel chemotherapeutic target.     

多共振分量融合CNN的行星齿轮箱故障诊断

针对行星齿轮箱中各部件所激起的振动成分混叠、早期故障特征经常被较强的各级齿轮谐波成分以及环境噪声所湮没的问题，提出一种多共振分量融合卷积神经网络（multi-resonance component fusion based convolutional neural network，简称MRCF-CNN）的行星齿轮箱故障诊断方法。首先，对振动信号进行共振稀疏分解，得到包含齿轮谐波成分的高共振分量和可能包含轴承故障冲击成分的低共振分量；其次，构建多共振分量融合卷积神经网络，将得到的高、低共振分量和原始振动信号进行自适应的特征级融合，通过有监督的方式训练模型并进行行星齿轮箱故障诊断。对行星齿轮箱实验数据的分析结果表明，该方法能够有效分类行星齿轮箱中滚动轴承和齿轮的故障，成功对行星齿轮箱故障进行诊断，同时能够进一步增强卷积神经网络对振动信号所蕴含的故障信息的辨识能力。     

锂化合物对硫铝酸盐水泥性能的影响分析

硫铝酸盐水泥是近年来广受关注的重要低碳水泥品种,在快速修补和防渗堵漏应用中,需要掺入适宜的促凝剂来满足施工要求.研究了两种锂化合物对硫铝酸盐水泥凝结时间、强度的影响规律,并采用XRD和SEM手段分析水泥水化产物.结果表明,当掺入两种锂化合物之后,硫铝酸盐水泥的凝结时间有明显的降低,并且Li2 CO3对硫铝酸盐水泥的促凝作用比LiOH·H2 O更为显著;硫铝酸盐水泥的小时强度随着Li2 CO3掺量的增加而明显提高,LiOH·H2 O对水泥小时强度的影响并不明显,两种锂化合物均会降低水泥的后期强度;从水化产物的微观分析来看,硫铝酸盐水泥的水化产物种类并不会因掺加锂化合物而有所改变,Li2 CO3对硫铝酸盐水泥的1 d水化有所促进,而LiOH·H2 O不会对水化产物产生明显影响.     

Preparation and polymerization of isopimaric acid derivatives

Isopimaric acid is a typical rosin compound and can account for 30% of the total mass of slash pine rosin. The molecular structure of isopimaric acid derivatives features an unsaturated double bond at the C13 position, opening up the possibility of their industrial polymerization. In this study, isopimaric acid (95.4%), methyl isopimarate (99.5%), and allyl isopimarate (95.1%) were prepared as highly pure monomers. New experimental results are presented and mechanisms based on the investigation of free-radical polymerization under UV irradiation are proposed. New rosin monomers for potential value-added utilization of woody biomass are also identified. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019 , 136, 47817.     

Dynamic Stabilization of DNA Assembly by Using Pyrrole-Imidazole Polyamide

We used N-methylpyrrole (Py)-N-methylimidazole-(Im) polyamide as an exogenous agent to modulate the formation of DNA assemblies at specific double-stranded sequences. The concept was demonstrated on the hybridization chain reaction that forms linear DNA. Through a series of melting curve analyses, we demonstrated that the binding of Py−Im polyamide positively influenced both the HCR initiation and elongation steps. In particular, Py−Im polyamide was found to drastically stabilize the DNA duplex such that its thermal stability approached that of an equivalent hairpin structure. Also, the polyamide served as an anchor between hairpin pairs in the HCR assembly, thus improving the originally weak interstrand stability. We hope that these proof-of-concept results can inspire future use of Py−Im polyamide as a molecular tool to modulate the formation of DNA assemblies.     

FDC在TFT-LCD中的应用案例研究

针对x因子不明确的品质不良,以TFT-LCD某产品不良为例,提出了FDC大数据分析方法。与实际生产过程相结合,经过数据收集和过滤、数据降维和主成分分析过程,找到该品质不良的强相关因子。通过对强关联因子进行DOE实验设计,明确关键因子管控线,提高产品生产力。     

Experimental Study on Damage Mechanism of Basalt Fiber Reinforced Mortar Based on Acoustic Emission Wavelet Energy Spectrum Analysis

Russian Journal of Nondestructive Testing - To investigate the effect of basalt fiber on the fracturing process and damage mechanism of cement-based materials under axial compression, acoustic...